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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study under GLP with minor deviations.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
yes
Principles of method if other than guideline:
concentration factor = 10
highest concentration = 500 mg/l
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Octylamine
EC Number:
203-916-0
EC Name:
Octylamine
Cas Number:
111-86-4
Molecular formula:
C8H19N
IUPAC Name:
octan-1-amine

Sampling and analysis

Details on sampling:
Before filling into test bassins under continous stirring the test substance was mixed with dilution water and homogenized by Ultra-Turrax.


Testing approach was as a solution to turbidity. At all concentrations tested
no segregation could be observed from the ground and educational bodies.


10 - 100 mg / l, the pH value after the substance was added at 8.6 to 11.5. he was
adjusted with 1N HCl to the pH of the water test.

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Test temperature:
22±1°C
pH:
8-8.2
Dissolved oxygen:
≥80% of the saturation value
Nominal and measured concentrations:
0 / 1 / 10 / 100 und 500 mg/l
Details on test conditions:
The experiment was carried out in 2 parts. Per experimental group 10 fish were used.
1. test: concentrations: 0 + 500 mg/l
2. test: concentrations 0 / 1 / 10 / 100 mg/l

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
1 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
10 - 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
10 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Applicant's summary and conclusion

Conclusions:
The LC50 (96h) to fish (Danio rerio) according to OECD203 study of the substance is in the range of 10-100 mg/l.
Executive summary:

The LC50 (96h) to fish (Danio rerio) according to OECD203 study of the substance is in the range of 10-100 mg/l.