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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according to OECD/EU guideline

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
ethyl 1-[2-(2,4-dichlorophenyl)acetoxy]cyclohexanecarboxylate
Cas Number:
361366-16-7
Molecular formula:
C17H20Cl2O4
IUPAC Name:
ethyl 1-[2-(2,4-dichlorophenyl)acetoxy]cyclohexanecarboxylate
Radiolabelling:
no

Study design

Analytical monitoring:
yes

Results and discussion

Transformation products:
not measured
Dissipation DT50 of parent compoundopen allclose all
pH:
9
Temp.:
25 °C
Hydrolysis rate constant:
0 s-1
DT50:
2 403 h
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other: Arrhenius equation
pH:
9
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
99.8 h
Type:
(pseudo-)first order (= half-life)
pH:
9
Temp.:
65 °C
Hydrolysis rate constant:
0 s-1
DT50:
21.5 h
Type:
(pseudo-)first order (= half-life)
pH:
9
Temp.:
80 °C
Hydrolysis rate constant:
0 s-1
DT50:
4.13 h
Type:
(pseudo-)first order (= half-life)

Any other information on results incl. tables

-At pH value = 7 and 50 °C: Preliminary test: Within five days the degradation was less than 10%

-At pH value = 4 and 50 °C: Preliminary test: Within five days the degradation was less than 10%

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The test substance is degradable according to EG guideline C.7 92/69 (OECD 111) at pH 9.
The substance is not degradable at pH 7 and pH4.