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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 1994, november 4th to 1994, december 22nd
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study performed according to requirements of the Annex to European Commission Directive 92/69/EEC

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report date:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
GLP compliance:
yes
Type of distribution:
counted distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
3',5'-dichloro-4'-ethyl-2'-hydroxypalmitanilide
EC Number:
406-200-8
EC Name:
3',5'-dichloro-4'-ethyl-2'-hydroxypalmitanilide
Cas Number:
117827-06-2
Molecular formula:
C24H39Cl2NO2
IUPAC Name:
N-(3,5-dichloro-4-ethyl-2-hydroxyphenyl)hexadecanamide
Details on test material:
A consignment of M-3221 (300g net weignt) was received at Pharmaco LSR on 26 july 1994.
The test material was identified by the batch number 944002. It was stored at ambient temperature, protected from light, in the original container.
The following information concerning the test material was provided by the Sponsor.
Code name: M-3221
Chemical name: 2,4-dichloro-3-ethyl-6-hexadecanoyl aminophenol
Relative molar mass: 444.5
Physical state: Solid
Batch number: 944002
Use: industrial chemical

Results and discussion

Particle size
Percentile:
D50
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Particle size distribution at different passagesopen allclose all
No.:
#1
Size:
> 400 µm
Distribution:
95.7 %
No.:
#2
Size:
>= 125 - < 400 µm
Distribution:
3.1 %
No.:
#3
Size:
>= 75 - < 125 µm
Distribution:
0.9 %
No.:
#4
Size:
>= 30 - < 75 µm
Distribution:
0.2 %
No.:
#5
Size:
>= 10 - < 30 µm
Distribution:
>= 0 - < 0.1 %
No.:
#6
Size:
>= 0 - < 10 µm
Distribution:
>= 0 - < 0.1 %

Applicant's summary and conclusion

Conclusions:
Less than 10% by mass of particles were found to pass a 400µm sieve and less than 0.1% passed a sieve of 30µm aperture.