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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December 16, 2011 - January 27, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study has been performed according to OECD and EU Method guidelines and in compliance with GLP principles.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
(O.J. no L220, 2009)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
(2006)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
(1996)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Constituent 1
Chemical structure
Reference substance name:
N-cyclohexylcyclohexanaminium (2S)-4-fluoro-4-methyl-2-{[(1S)-2,2,2-trifluoro-1-{4'-methanesulfonyl-[1,1'-biphenyl]-4-yl}ethyl]amino}pentanoate
EC Number:
700-778-8
Cas Number:
1064076-86-3
Molecular formula:
C21H23F4NO4S.C12H23N
IUPAC Name:
N-cyclohexylcyclohexanaminium (2S)-4-fluoro-4-methyl-2-{[(1S)-2,2,2-trifluoro-1-{4'-methanesulfonyl-[1,1'-biphenyl]-4-yl}ethyl]amino}pentanoate
Details on test material:
- Name of test material (as cited in study report): Biphenyl DCHA Salt
- Description: White powder

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
< 0.002 Pa
Remarks on result:
other: atmospheric pressure
Temp.:
25 °C
Vapour pressure:
< 0.006 Pa
Remarks on result:
other: atmospheric pressure

Any other information on results incl. tables

At temperatures ≥150°C, weight loss curves were not linear and could therefore not be used to determine vapour pressure at 20°C and 25°C. At lower temperatures, weight loss curves were linear but weight loss was not sufficient to determine vapour pressure accurately. The weight loss of the test substance at 110°C, 120°C, 130°C and 140°C however was lower than the weight loss of hexachlorobenzene at the same temperatures. Based on this, the vapour pressure of the test substance is reported to be below that of hexachlorobenzene.

 

20°C

25°C

[Pa]

[mm Hg]

[Pa]

[mm Hg]

Test substance

< 1.5 x 10-3

< 1.1 x 10-5

< 5.8 x 10-3

< 4.3 x 10-5

Applicant's summary and conclusion

Conclusions:
The isothermal TGA effusion method was applied for the determination of the vapour pressure of Biphenyl DCHA Salt. The vapour pressure of the test substance at 20°C (293K) was < 1.5 x 10^-3 Pa (= < 1.1 x 10^-5 mm Hg) and the vapour pressure at 25°C (298K) was < 5.8 x 10^-3 Pa (= < 4.3 x 10^-5 mm Hg).