Registration Dossier
Registration Dossier
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EC number: 253-211-7 | CAS number: 36788-39-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- GLP compliance:
- yes
- Test type:
- acute toxic class method
- Limit test:
- yes
Test material
- Reference substance name:
- 7-[2-(2-hydroxymethylethoxy)methylethoxy]tetramethyl-3,6,8,11-tetraoxa-7-phosphatridecane-1,13-diol
- EC Number:
- 253-211-7
- EC Name:
- 7-[2-(2-hydroxymethylethoxy)methylethoxy]tetramethyl-3,6,8,11-tetraoxa-7-phosphatridecane-1,13-diol
- Cas Number:
- 36788-39-3
- Molecular formula:
- C18H39O9P
- IUPAC Name:
- 7-[2-(2-hydroxymethylethoxy)methylethoxy]tetramethyl-3,6,8,11-tetraoxa-7-phosphatridecane-1,13-diol
- Test material form:
- other: liquid
- Details on test material:
- Niax Color Stabilizer CS-22
Batch: 465692
Purity: 95%
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- HanBrl: Wistar (SPF) female rats3 animals per group6 total female ratsAge when treated: 12 weeks
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Details on oral exposure:
- Administered undiluated via oral gavage at a volume of 1.82 ml/kg
- Doses:
- 2000 mg/kg
- No. of animals per sex per dose:
- 3
- Control animals:
- no
- Details on study design:
- two separate groups of 3 female rats (6 rats total) were treated with 2000 mg/kg of the test material via oral gavage (undiluted). The animals were observed for 14 days post expsoure.
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: no mortality at limit dose of 2000 mg/kg
- Mortality:
- None
- Clinical signs:
- other: None
- Gross pathology:
- No macroscopic findings were recorded at necropsy.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated informationCriteria used for interpretation of results: EU
- Conclusions:
- There was no mortality in any of the test animals at the limit dose of 2000 mg/kg bw. The substance is not considered to be acutely toxic via oral gavage.
- Executive summary:
There was no mortality in any of the test animals at the limit dose of 2000 mg/kg bw. The substance is not considered to be acutely toxic via oral gavage.
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