Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 611-342-0 | CAS number: 55974-25-9
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study (OECD 202) but full details are not available. Therefore the reliability is with restricitions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 7-methoxy-4,4-dimethyl-3,4-dihydro-1H-2-benzopyran-1,3-dione
- EC Number:
- 611-342-0
- Cas Number:
- 55974-25-9
- Molecular formula:
- C12 H12 O4
- IUPAC Name:
- 7-methoxy-4,4-dimethyl-3,4-dihydro-1H-2-benzopyran-1,3-dione
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): Isochroman puro
- Physical state: powder
- Lot/batch No.: 01002
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 167.94 mg/L
- Test temperature:
- 18 - 22 °C +- 1 °C
- pH:
- 7.0
- Dissolved oxygen:
- not upper 60 %
- Reference substance (positive control):
- yes
- Remarks:
- dichromate
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In conclusion, Isochroman puro is considered to be a highly toxic to Daphnia magna under the conditions of this study ( i.e. EC50 100 mg/l).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
