Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 817-828-0 | CAS number: 80322-82-3
Endpoint summary
Administrative data
Description of key information
Short-term EC50 values for Triethylene glycol dimethanesulfonate (CAS no. 80322-82-3) are available for two trophic levels of the aquatic freshwater compartment (aquatic invertebrates, algae) from GLP studies according to OECD 201 and OECD 202.
Growth inhibition study aquatic algae (Raphidocelis subcapitata) (OECD 201):
ErC50 (72h): >100 mg/l nominal concentration
NOErC (72h): 10 mg/l nominal concentration
Short term toxicity on invertebrates (Daphnia magna) (OECD 202):
EC50 (48h): >100 mg/l nominal concentration
NOEC (48h): 100 mg/l nominal concentration
Additional information
Algae:
The acute toxicity of Triethylene glycol dimethanesulfonate (CAS no. 80322-82-3) to the green alga Raphidocelis subcapitata was determined in a 72-hour static test according to OECD guideline 201. The median effect concentrations (EC50) of Triethylene glycol dimethanesulfonate on the green alga Raphidocelis subcapitata was estimated to be >100 mg/l nominal concentration after 72 h of exposure. The NOEC value was determined to be 10 mg/l nominal concentration after 72 h of exposure. The results of the test can be considered reliable without restriction.
Daphnia:
The acute toxicity of Triethylene glycol dimethanesulfonate (CAS no. 80322-82-3) to Daphnia magna was determined in a 48-hour static test according to OECD guideline 202. The median effect concentrations (EC50) Triethylene glycol dimethanesulfonate on Daphnia magna were estimated to be >100 mg/l nominal concentration after 24 and 48 h of exposure. The NOEC values were determined to be 100 mg/l nominal concentration after 24 and 48 h of exposure. The results of the test can be considered reliable without restriction.
Conclusion on classification
The environmental classification of Triethylene glycol dimethanesulfonate (CAS no. 80322-82-3) is currently not harmonised according to the CLP Regulation (EC) 1272/2008. Based on available acute aquatic toxicity data, the lowest valid effect concentration for freshwater aquatic organisms is >100 mg/L (EC50 for algae or aquatic invertebrates). Based on the available acute data, the substance should not be classified for acute toxicity following Annex I, table 4.1.0a of the CLP regulation (there are no acute values ≤ 1 mg/L). The substance Triethylene glycol dimethanesulfonate (CAS no. 80322-82-3) is not readily biodegradable. Based on the lowest valid effect concentration for invertebrates or algae (Daphnia magna / Raphidocelis subcapitata, EC50 >100 mg/L), the substance should not be classified for chronic aquatic toxicity, following Annex I, table 4.1.0b iii of the CLP regulation (there are no acute values ≤ 100 mg/l).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
