Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 Jan 2021 to 17 Mar 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Version / remarks:
- 2012, October 2
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Version / remarks:
- March 04, 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Version / remarks:
- June 2002
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- air comparison pycnometer (for solids)
Test material
- Reference substance name:
- N-[4-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]pyrimidin-2-yl]-6-methoxy-4-(morpholin-4-yl)benzene-1,3-diamine
- Cas Number:
- 1903009-56-2
- Molecular formula:
- C27H32N8O2
- IUPAC Name:
- N-[4-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]pyrimidin-2-yl]-6-methoxy-4-(morpholin-4-yl)benzene-1,3-diamine
- Test material form:
- solid: particulate/powder
1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Batch (Lot) Number: I20ID2980
- Purity/Composition: 95.0%
- Purity/Composition correction factor: 1.0
- Purity test date : 2020-10-26
- Expiry date: 17 September 2022 (retest date)
- Physical Description: Beige powder
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Final preparation of a solid: prior to use in the study, the test material was dried in a desiccator under vacuum using silicagel as the drying agent at 22.8 ± 0.4°C in dark for 43.5 hours.
Results and discussion
Densityopen allclose all
- Key result
- Type:
- density
- Density:
- 1.27 g/cm³
- Temp.:
- 20 °C
- Type:
- relative density
- Density:
- 1.27
- Temp.:
- 20 °C
Any other information on results incl. tables
The results of the tests on the determination of the density of the test item are given in the table below
| Test 1 | Test 2 | |
Sample mass (g) | 2.0706 | 2.2051 | |
Sample volume (cm3) | 1.6266 1.6355 1.6362 1.6350 1.6301 | 1.7391 1.7411 1.7444 1.7420 1.7418 | |
Average volume cm3) | 1.6327 ± 0.0037 | 1.7417 ± 0.0017 | |
Density (g/cm3) | 1.2682 | 1.2661 | |
Mean Density (g/cm3) | 1.27 |
| |
Applicant's summary and conclusion
- Conclusions:
- A gas comparison stereopycnometer was used for the determination of the density and relative density of JNJ-73848281-AAA (T003904).
The density of the test item at 20ºC was 1.27 g/cm3 (1.27E3 kg/m3).
The relative density was 1.27.
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