Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie. Vol. 6B, Pg. 183, 1951.
Year:
1951
Bibliographic source:
ChemIDplus database

Materials and methods

Principles of method if other than guideline:
method not published
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl p-aminosalicylate
EC Number:
223-958-3
EC Name:
Methyl p-aminosalicylate
Cas Number:
4136-97-4
Molecular formula:
C8H9NO3
IUPAC Name:
methyl 4-amino-2-hydroxybenzoate

Test animals

Species:
mouse

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion