Registration Dossier
Registration Dossier
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EC number: 428-790-6 | CAS number: 72963-72-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- other: Study summary provided by ECHA
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- The test method does not comply entirely with Annex V guidelines, but the information it provides was judget satisfactory for classification purposes.
Data source
Reference
- Reference Type:
- other: Study summary provided by ECHA
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 72-2 (Aquatic Invertebrate Acute Toxicity Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 428-790-6
- EC Name:
- -
- Cas Number:
- 72963-72-5
- Molecular formula:
- C17H22N2O4
- IUPAC Name:
- [2,5-dioxo-3-(prop-2-yn-1-yl)imidazolidin-1-yl]methyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate; [2,5-dioxo-3-(prop-2-yn-1-yl)imidazolidin-1-yl]methyl (1R,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
- Test material form:
- liquid: viscous
- Details on test material:
- Name: Imiprothrin
Appearance: viscous liquid
Colour: amber
Constituent 1
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- A stock solution was prepared by dissolving the test compound in dimethylformamide (DMF).
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- Water hardness ranged between 162-170 mg CaCO3/l
- Nominal and measured concentrations:
- The nominal duplicate test concentrations for this study were 0.020, 0.032, 0.054, 0.090 and 0.15 mg/l.
The mean measured test concentrations were 0.013, 0.030, 0.049, 0.082 and 0.16 mg/l, respectively.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.03 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 0.082 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.051 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.098 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.16 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.056 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Details on results:
- All results were based on the mean measured test concentrations.
The 48 hour LC50 value was 0.056 mg/L, with 95% confidence limits of 0.049 and 0.082 mg/l.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
