Registration Dossier
Registration Dossier
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EC number: 701-333-0 | CAS number: -
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in chemico
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- QSAR
- GLP compliance:
- no
Test material
- Reference substance name:
- Reaction products of 2,2-dimethylpropane-1,3-diol with 1-chloro-2,3-epoxypropane
- EC Number:
- 701-333-0
- Molecular formula:
- C11H20O4
- IUPAC Name:
- Reaction products of 2,2-dimethylpropane-1,3-diol with 1-chloro-2,3-epoxypropane
- Details on test material:
- It is a UVCB substance.
1
In chemico test system
- Details on the study design:
- See it in the attachement.
Results and discussion
In vitro / in chemico
Results
- Key result
- Remarks on result:
- not measured/tested
- Remarks:
- It is a QSAR prediction
- Other effects / acceptance of results:
- QSAR
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (skin sensitising) based on GHS criteria
- Conclusions:
- According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may cause an allergic skin reaction (H317 Skin Sens.1).
- Executive summary:
According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may cause an allergic skin reaction (H317 Skin Sens.1).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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