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Physical & Chemical properties

Vapour pressure

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Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
2000
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Guideline study (EU A.4) in compliance with GLP. However, the substance is a reaction mixture, and thus probably water, 2-hydroxy­propylamine and/or formaldehyde had been measured in the gas phase, and therefore the vapour pressure cannot be attributed to an individual constituent.
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
yes (incl. QA statement)
Remarks:
Jai Research Foundation
Type of method:
static method
Temp.:
25 °C
Vapour pressure:
5.83 hPa
Remarks on result:
other: Vapour pressure determined at 30, 40, 50 and 60°C; value for 25°C calculated from regression curve. Probably water, HPA and/or formaldehyde measured.
Conclusions:
The vapour pressure analysed according to guideline EU A.4 was 5.83 hPa at 25°C. However, the substance is a reaction mixture, and thus probably water, 2-hydroxy­propylamine and/or formaldehyde had been measured in the gas phase, and therefore the vapour pressure cannot be attributed to an individual constituent.
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
2001
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Guideline study (EU A.4) in compliance with GLP. However, the substance is a reaction mixture, and thus probably water, 2-hydroxy­propylamine and/or formaldehyde had been measured in the gas phase, and therefore the vapour pressure cannot be attributed to an individual constituent.
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
yes (incl. QA statement)
Remarks:
Siemens AG
Type of method:
dynamic method
Temp.:
20 °C
Vapour pressure:
2 hPa
Remarks on result:
other: Exothermal decomposition at 180 – 290°C. VP measured in temp. range 50.8 – 86.5°C. Probably water, HPA and/or formaldehyde measured.
Temp.:
25 °C
Vapour pressure:
2.8 hPa
Remarks on result:
other: Exothermal decomposition at 180 – 290°C. VP measured in temp. range 50.8 – 86.5°C. Probably water, HPA and/or formaldehyde measured.
Temp.:
50 °C
Vapour pressure:
13.9 hPa
Remarks on result:
other: Exothermal decomposition at 180 – 290°C. VP measured in temp. range 50.8 – 86.5°C. Probably water, HPA and/or formaldehyde measured.
Transition / decomposition:
yes
Transition temp.:
>= 180 - <= 290 °C
Conclusions:
The vapour pressure analysed according to guideline EU A.4 was 2.8 hPa at 25°C. However, the substance is a reaction mixture, and thus probably water, 2-hydroxy­propylamine and/or formaldehyde had been measured in the gas phase, and therefore the vapour pressure cannot be attributed to an individual constituent.
Endpoint:
vapour pressure
Type of information:
calculation (if not (Q)SAR)
Remarks:
estimated by calculation
Adequacy of study:
other information
Study period:
2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Remarks:
Generally accepted calculation method
Temp.:
25 °C
Vapour pressure:
0.014 hPa
Remarks on result:
other: Value for 25 °C calculated with Epi Suite 3.12, MPBPWIN v1.41.
Temp.:
20 °C
Vapour pressure:
0.01 hPa
Remarks on result:
other: Value for 20 °C estimated with EUSES (Generally accepted model calculation)
Conclusions:
The vapour pressure calculated with MPBPWIN v1.41 (Epi Suite) resulted in a value of 0.014 hPa at 25°C .

Description of key information

The vapour pressure calculated with MPBPWIN v1.41 (Epi Suite) resulted in a value of 0.014  hPa at 25°C . The vapour pressure was determined experimentally by two studies according to guideline EU A.4 resulting in 5.83 hPa (Schülke & Mayr)  and 2.8 hPa (Bode) at 25°C.

Key value for chemical safety assessment

Vapour pressure:
0.014 hPa
at the temperature of:
25 °C

Additional information

The vapour pressure of the substance was determined experimentally by two studies, resulting in 5.83 hPa and 2.8 hPa at 25°C. However,the substance is a reaction mixture. Thus, probably water, 2-hydroxy­propylamine and/or formaldehyde had been measured in the gas phase, and therefore the vapour pressure cannot be attributed to an individual constituent. In contrast to the experimental results, the calculated value for the main constituent 3,3’-methylene-bis[5-methyl-oxazolidine] (0.014 hPa at 25°C) is lower by several orders of magnitude. For exposure calculations, the calculated value of the main constituent is used as the most appropriate estimation.