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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
10.08.2011 - 20.09.2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
> 6.5
Temp.:
25 °C
Remarks on result:
other: pH not measured/not relevant

Based preliminary evaluation of the log Pow (> 2.8) the partition coefficient n-octanol/water of the test item at room temperature was determined by the HPLC-method

The partition coefficient Pow was estimated from the saturation concentrations in n-octanol and water.

Conclusions:
The partition coefficient of the test substance was > 6.5.
Executive summary:

The partition coefficient n-octanol/water of the test item was determined according to the "HPLC- method" described in the European Commission Regulation (EC) No. 440/2008. The partition coefficient of the test substance was > 6.5.

Description of key information

The partition coefficient of the test substance was > 6.5.

Key value for chemical safety assessment

Additional information