Isooctyl palmitate

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2019

Report date:

2019

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Isooctyl palmitate

EC Number:

215-675-9

EC Name:

Isooctyl palmitate

Cas Number:

1341-38-4

Molecular formula:

C24H48O2

IUPAC Name:

6-methylheptyl hexadecanoate

Test material form:

liquid

Remarks:

a colourless liquid

Study design

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, domestic, adapted

Details on inoculum:

Activated sludge from a biologic sewage treatment plant was used as inoculum. The cho-sen plant treats mostly domestic sewage.

Duration of test (contact time):

ca. 28 d

Results and discussion

% Degradation

Parameter:

% degradation (O2 consumption)

Value:

ca. 73

Sampling time:

28 d

Details on results:

•The test item 1341-38-4 Isooctyl palmitate is considered as “readily biodegradable“.
•The degree of biodegradation reached 73 % after 28 days.
•The 10-day-window began on day 2, at its end, 61 % degradation were reached, surpassing the pass level of 60 % given in the OECD guideline.
•The abiotic degradation reached 1 %.

Any other information on results incl. tables

All validity criteria were met.

Degradation behaviour of positive control and toxicity control was normal. Abiotic degradation reached 1 %. Both replicates of the test item showed very good correspondence.

If degradation in the toxicity flask is below 25 % after 14 days, the test item can be considered as toxic towards the inoculum. As degradation in the toxicity flask was 83 % after 14 days, the test item can be stated as “not toxic towards the inoculum in a concentration of 25.6 mg/L”.

For pure substances ready biodegradability is defined in the guidelines as degradation reaching the pass level of 60 % within 10 days after reaching a level of 10 %.

The degradation was 61 % at the end of the 10-day-window.

Therefore,1341-38-4 Isooctyl palmitate is considered as “readily biodegradable”

No observations were made which might cause doubts concerning the validity of the study outcome.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

When applying the 10-day-window, 1341-38-4 Isooctyl palmitate is readily bio-degradable following OECD 301B and EU C.4-C respectively.