Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine (1:2)

Adsorption / desorption

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

adsorption / desorption: screening

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter

Reference 2

Endpoint:

adsorption / desorption

Remarks:

adsorption

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2009

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Two QSAR estimations are performed. One is described in the EU Technical Guidance Document, the other is used by the UDS EPA.

Principles of method if other than guideline:

QSAR estimation by 2 methods.

GLP compliance:

no

Type of method:

other: QSAR

Radiolabelling:

no

Test temperature:

Not relevant.

Analytical monitoring:

not required

Details on sampling:

Not relevant.

Details on matrix:

Not relevant.

Details on test conditions:

Not relevant.

Computational methods:

Adsorption coefficient per organic carbon (Koc):

1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines: logKoc = 0.30 logKow + 1.5 and logKow = -1.22.
Result: logKoc = 1.13.

2) Using the programme KOCWIN v2.00:
Result based on molecular connectivity index: logKoc = 1.51.
(Result based on a calculated logKow of -1.37: logKoc = 0.0002.)

Type:

log Koc

Value:

1.13

Adsorption coefficient per organic carbon (Koc):

1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines:

logKoc = 0.30 logKow + 1.5 and logKow = -1.22: -> logKoc = 1.13.

2) Using the programme KOCWIN v2.00:

Based on molecular connectivity index: logKoc = 1.51.

(Based on a calculated logKow of -1.37: logKoc = 0.0002.)

Conclusions:

Melamine has an estimated low ability to adsorb to soil.

Executive summary:

Adsorption coefficient per organic carbon (Koc):

1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines: logKoc = 0.30 logKow + 1.5 and logKow = -1.22

Result: logKoc = 1.13.

2) Using the programme KOCWIN v2.00:

Result: logKoc = 1.51.

Reference 3

Endpoint:

adsorption / desorption: screening

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

Please refer to the analogue justification attached to section 13

Reason / purpose for cross-reference:

read-across source

Type:

log Koc

Value:

1.13 dimensionless

Remarks on result:

other: Source, Supporting, RA-A, CAS 108-78-1, QSAR.

Additional information

Experimental data on the transport of diphosphoric acid, compound with 1,3,5-triamine (1:2) are not available. Based on the experimentally determined low log Pow of the substance (log Pow -1.24 at 20 °C, OECD 107) a low adsorption potential of the substance is expected.