Reaction mass of (-)δ decenolactone and (-)δ dodecenolactone

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

February and March 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method. No deviation affected the quality of the study. The substance is considered to be adequately characterised with composition. Therefore validation applies without restrictions.

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

July, 27, 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

Regulation (EC) n°440/2008

Deviations:

no

GLP compliance:

no

Remarks:

not required for physchem data, unless relating to CLP

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 293.4 - <= 295.3 °C

Atm. press.:

>= 100.2 - <= 100.3 kPa

Decomposition:

no

Assay 1: 294.4°C at 100.2 kPa

Assay 2: 295.3°C at 100.2 kPa

Assay 3: 293.4°C at 100.3 kPa

In the boiling point determination, a single endothermic signal was recorded. The peak profiles are a little spread, this may be due to the complex nature of the substance, and/or size of the hole in the commercial crucible top which generates a little evaporation before the boiling point. This early evaporation does not impact the accuracy of the boiling point since it is determined at the peak maximum.

The triplicate determinations are out of the estimated accuracy of +/-0.5°C (according to the guidelines) at the same atmospheric pressure of 100.2-100.3 kPa; therefore a range is stated for the boiling transition. This is also consistent with the complex nature, since this result may vary slightly with the substance composition.

For each boiling point assay, the crucible is weighted before and after filling and after measurement to validate that all the sample is vaporized. The weights of the three crucibles are the same before filling and after measurement, the test item is totally (>98.5%) evaporated during the measurement.

Executive summary:

The boiling point of the test substance was determined according to OECD103/EU A.2 guideline, using Differential Scanning Calorimetry method.

Three main runs were performed, under nitrogen flow; since results were out of accuracy and the substance is a multi-constituent, the range of peak temperatures was retained.

The boiling range of the test substance has been determined to be 293.4 - 295.3 °C.

Description of key information

Experimental boiling range under N2 = 293,4 - 295,3 °C at 100,2-100,3 kPa (not corrected to normal atmP).

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method, is available. It is considered as a key study. Since the result is expressed as a range, it is not used as key data (if needed, the initial bp, i.e. lower value of the range, could be retained).