Sodium octane-1-sulphonate monohydrate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

09 October 2017 - 27 October 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

Study was not conducted under GLP conditions and are some (non-critical) reporting deficiencies with respect to guideline requirements. The experimental values obtained from this study are deemed to be reliable with acceptable restrictions.

Qualifier:

according to guideline

Guideline:

other: ISO 4311:1979

Version / remarks:

June 1979

Deviations:

yes

Remarks:

Some minor, non-critical, deviations from guideline reporting requirements were noted in the final report. These deviations are not considered sufficient to invalidate the results of the study.

GLP compliance:

no

Type of method:

other: Critical micelle concentration

Remarks:

CMC is being used as a surrogate water solubility value as the test item is surface active.

Key result

Water solubility:

9.836 g/L

Conc. based on:

test mat.

Temp.:

20 °C

Remarks on result:

other: Mean value

Remarks:

Obtained using determination 1 and determination 2.

Water solubility:

9.88 g/L

Conc. based on:

test mat.

Temp.:

20 °C

Remarks on result:

other: Determination 1

Water solubility:

9.792 g/L

Conc. based on:

test mat.

Temp.:

20 °C

Remarks on result:

other: Determination 2

Results:

 

Table 2:          Test Item Critical Micelle Concentration

Test Number:	Measured CMC (mg/l)
1	9,880.337
2	9,792.494
Mean	9,836.416

 

Conclusions:

The critical micelle concentration of the the test item was determined to be 9.836 g/l at 20 °C ± 1 °C.

Executive summary:

ISO 4311:1979 – The critical micelle concentration of the test item was determined using the ring method.  The procedure was employed as a surrogate water solubility value because the test item is surface active.

A 50ml of the sample of test item in solution (concentration 30 g/l) was placed in the solutions was placed in the sample vessel.  Constant quantities of pure water (demineralised) were added in a stepwise manner to the sample.  A surface tension value at each concentration was determined.  Regression analysis was applied to recorded values and used to determine the crucial micelle concentration of the test item.  Determination of the critical micelle concentration was carried out in duplicate.

The mean crucial micelle concentration of the test item was determined to be 9.836 g/l at 20 °C ± 1 °C.

Description of key information

Critical micelle concentration: 9.836 g/l at 20^oC ± 1^oC; ISO 4311:1979; Anon. (2017).

Key value for chemical safety assessment

Water solubility:

9.836 g/L

at the temperature of:

20 °C

Additional information

ISO 4311:1979 – The critical micelle concentration of the test item was determined using the ring method.  The procedure was employed as a surrogate water solubility value because the test item is surface active.

A 50ml of the sample of test item in solution (concentration 30 g/l) was placed in the solutions was placed in the sample vessel.  Constant quantities of pure water (demineralised) were added in a stepwise manner to the sample.  A surface tension value at each concentration was determined.  Regression analysis was applied to recorded values and used to determine the crucial micelle concentration of the test item.  Determination of the critical micelle concentration was carried out in duplicate.

The mean crucial micelle concentration of the test item was determined to be 9.836 g/l at 20 °C ± 1 °C.