Registration Dossier
Registration Dossier
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EC number: 213-485-0 | CAS number: 957-68-6
Respiratory sensitisation
Administrative data
- Endpoint:
- respiratory sensitisation: in vivo
- Type of information:
- other: Case reports from workers.
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Case reports, having only the abstracts.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Asthma in workers manufacturing cephalosporins
- Author:
- Coutts et al.
- Year:
- 1 981
- Bibliographic source:
- Br. Med. J.; VOL 283 ISS Oct 10 1981, P950, (REF 4)
- Reference Type:
- publication
- Title:
- Bronchial asthma due to 7-aminocephalosporanic acid in workers employed in cephalosporine production
- Author:
- Briatico-Vangosa G et al.
- Year:
- 1 981
- Bibliographic source:
- Medicina del lavoro Nov.-Dec. 1981, Vol.72, No.6, p.488-493
- Reference Type:
- publication
- Title:
- Occupational asthma caused by cefmetazole and 7-aminocephalosporanic acid: description of a clinical case
- Author:
- Fracchia G et al.
- Year:
- 1 996
- Bibliographic source:
- G Ital Med Lav. 1996 Jan-May; 13-5. [G italiano dliano di medicina del l del lavoro]
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Reporting of cases.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- EC Number:
- 213-485-0
- EC Name:
- 3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Cas Number:
- 957-68-6
- Molecular formula:
- C10H12N2O5S
- IUPAC Name:
- 3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (respiratory sensitising) based on GHS criteria
- Executive summary:
The test item is reported as being a respiratory sensitizer for workers.
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