Registration Dossier
Registration Dossier
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EC number: 205-287-8 | CAS number: 137-29-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018 72hours
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Remarks:
- ICP-MS
- Vehicle:
- no
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- TEST ORGANISM
- Common name: Alga
- Strain: Pseudokirchneriella subcapitata CCAP 278/4 Received 15 May 2018
- Source (laboratory, culture collection): Culture collection of Algae and Protozoa, SMAS Research services Ltd, Scottish marine institute, OBAN Argyll Scotland
- Age of inoculum (at test initiation):
- Method of cultivation: From a pre-culture growing in exponential phase, deionised water with added nutrients according to OECD 201
ACCLIMATION
- Acclimation period:
- Culturing media and conditions (same as test or not):
- Any deformed or abnormal cells observed: - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- Reference substance (positive control):
- no
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 - < 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.1 - < 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Basis for effect:
- other: Yield
- Validity criteria fulfilled:
- yes
- Conclusions:
- 72 hour EC50 by percent inhibition by yield and percent inhibition by growth rate were both in the range of 1-10mg/L
- Executive summary:
72 hour EC50 by percent inhibition by yield and percent inhibition by growth rate were both in the range of 1-10mg/L
Reference
Description of key information
EC50 for growth rate at 72 hours is 1.0 -10mg/L
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
