Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

Propane-1-thiol has a pKa of 10 and therefore is not expected to dissociate in the environment.

Key value for chemical safety assessment

pKa at 20°C:
10

Additional information

In accordance with REACH Chapter R.7A, this endpoint can be waived for ionisable substances with pKa greater than 10, as they will not tend to dissociate in water under normal environmental conditions. Propane-1-thiol has a pKa of 10 and therefore is not expected to dissociate in the environment. This SPARC online calculation is considered reliable and appropriate for use with this substance.