Registration Dossier
Registration Dossier
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Reaction mass of 1,5-Naphthalenedisulfonic acid, 3,3'-[(4-methyl-1,2-phenylene)bis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino[2-(acetylamino)-5-methoxy-4,1-phenylene]-2,1-diazenediyl]]bis-, sodium salt (1:4) and 1,5-Naphthalenedisulfonic acid, 3,3'-[(3-methyl-1,2-phenylene)bis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino[2-(acetylamino)-5-methoxy-4,1-phenylene]-2,1-diazenediyl]]bis-, sodium salt (1:4)
EC number: 947-857-5 | CAS number: -
Partition coefficient
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Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From March 18, 1989 to July 26, 1989
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EU Method A.8
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
Test material
- Test material form:
- solid
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- -3.2
- Temp.:
- 25 °C
- pH:
- > 6.42 - < 6.55
- Remarks on result:
- other: Average of 6 readings at three different concentrations
Any other information on results incl. tables
| Table 2: Readings | ||||||
| Sample | 1 | 2 | 3 | 4 | 5 | 6 |
| Absorbance 1 cm cell, 415 nm water phase | 0.297 | 0.625 | 0.314 | |||
| 0.298 | 0.612 | 0.300 | ||||
| Concentration in Water Phase (µg/mL) | 10861 | 5714 | 2871 | |||
| 10898 | 5595 | 2743 | ||||
| Absorbance 1 cm cell, 425 nm, n-Octanol Phase |
0.110 | 0.023 | 0.042 | |||
| 0.114 | 0.023 | 0.040 | ||||
| Concentration in n-Octanol Phase (µg/mL) | 9.0 | 1.2 | 5.7 | |||
| 9.4 | 1.2 | 5.5 | ||||
| Total Amount Detected (mg) | 162.9 | 28.6 | 57.4 | |||
| 163.5 | 28 | 54.9 | ||||
| Log P = Log (Concn. In n-Octanol Phase / Concn. In H2O Phase) | -3.0809 | -3.6778 | -2.6990 | |||
| -3.0655 | -3.6778 | -2.6990 | ||||
| Average Log P | -3.2 | |||||
| pH aquous Phase | 6.55 | Not tested | 6.42 | |||
Applicant's summary and conclusion
- Conclusions:
- Under the study conditions, the log Pow of the test substance was determined to be -3.2 at 25°C.
- Executive summary:
A study was conducted to determine the partition coefficient of the substance according to EU method A.8. Under the study conditions, the Log Pow of the test substance was determined to be -3.2 at 25 °C (Williams, 1989).
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