Registration Dossier
Registration Dossier
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EC number: 910-427-2 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The target substance Zinc peroxide and the source substances Zinc oxide, Zinc Chloride, Zinc sulfate, Zinc nitrate are ionic and consist of the Zinc2+ cation and the respective anion.
The read-across is based on the assumption that the zinc cation (as measure for dissolved zinc species) is the determining factor for (eco)toxicity.
For further details, see Justification for read-across attached to IUCLID chapter 13
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
See Justification for read-across attached to IUCLID chapter 13
3. ANALOGUE APPROACH JUSTIFICATION
See Justification for read-across attached to IUCLID chapter 13
4. DATA MATRIX
See Justification for read-across attached to IUCLID chapter 13 - Reason / purpose for cross-reference:
- read-across: supporting information
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
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- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- >= 0.068 - <= 2.909 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: Zn2+
- Basis for effect:
- mortality
- Conclusions:
- The 48 EC50 of Zn2+ ranged from 68 µg/L to 2.909 mg/L.
Reference
Description of key information
Key data (lowest EC50 values) are:
-for Ceriodaphnia dubia: 0.413 mg Zn/l (single value) at low pH and low hardness
-for Ceriodaphnia dubia: >0.53 mg Zn/l (single value) at low pH and high hardness
-for Ceriodaphnia dubia: 0.147 mg Zn/l (geomean value) at neutral/high pH and low hardness
-for Ceriodaphnia dubia: 0.228 mg Zn/l (geomean value) at neutral/high pH and high hardness
Key value for chemical safety assessment
Additional information
Many good quality and relevant data for 5 standard species. Tests were done according to standard protocol or equivalent.
Data are grouped per species according to
-pH: low (6 -<7) - neutral/high (7 -8.5)
-and hardness: low/medium (<100mg CaCO3/l) and medium/high (>100 mg CaCO3/l).
Ceriodaphnia dubia is for all test conditions the most sensitive species.
The available data on hydrogen peroxide show, that Zn2+ is the determining factor for ecotoxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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