Registration Dossier
Registration Dossier
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EC number: 231-203-4 | CAS number: 7446-26-6
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental data on the aquatic toxicity of dinzinc pyrophosphate are available for the three trophic levels fish, Daphnia and algae.
The available study on Danio rerio determined no acute toxic effects on fish (OECD 203). A LC50 (96 h) > 4.508 mg test item/L (geom. mean measured) was determined based on LC50(96 h) >1.948 mg Zn/L (geom. mean measured). The acute toxicity to aquatic invertebrates was tested in a study following OECD 202. The determined EC50(48 h) was26 mg test item/L (nominal). The most sensitive organisms are aquatic algae. In a study following OECD 201 conducted with Pseudokirchneriella subcapitata anEC50 (72 h) of 0.233 mg test item /L (meas. geom. mean) was determined. The reported EC10 (72 h) was 0.094 mg/test item/L (meas. geom. mean).
The assessment of the toxicity to microorganisms is based on a read-across approach. In accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006, read-across to the source substances calcium bis(dihydrogenorthophosphate)(CAS 7758-23-8) andzinc sulphate (CAS 7733-02-0)was conducted A detailed justification of the Analogue Approach is attached in IUCLID section 13.
An EC50(3 h) of 5.2 mg/L determined for the source substance zinc sulphate is used for the assessment. Detetrimental effects of phosphate to slugde microorganisms are not expected.
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