Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 907-653-9 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: chemicals are sharing very similar chemicall structure
- Justification for type of information:
- chemicals are sharing very similar chemicall structure
- Reason / purpose for cross-reference:
- read-across source
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 77
- Sampling time:
- 28 d
- Interpretation of results:
- readily biodegradable
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 32 d
- Reference substance:
- other: sodium benzoate
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 77
- Sampling time:
- 32 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 77
- Sampling time:
- 28 d
- Details on results:
- oxygen uptakes, as read on the SAPROMAT meters, are corrected:
-by deducting the basic oxygen updates of sludge (flasks 1/7 and 1/8)
-proportionally to account for the small differences between actual and nominal concentrations of test and reference substances
Degradation of sodium benzoate exceeds 40% after 7 days and 65% after 14 days: the activity of the inoculum is thus verified and the test is considered as valid - Interpretation of results:
- readily biodegradable
- Conclusions:
- camphor undergoes 77% biodegradation after 32 days (alos 77% after 28days) in the test conditions. Biodegradation starts on day 5 and reaches 67% at the end of the 10-day window (day 5to 15).
Thus, camphor should be regarded as readily biodegradable according to this test.
The curves obtained with the reference substance alone and with camphor+ reference show no toxic effect of camphor to the micro-organisms at the test concentration.
Referenceopen allclose all
| DAYS | 5 | 7 | 15 | 21 | 28 | 32 | |
| BOD sludge | 1st flask B1 | 8.0 | 10.0 | 12.0 | 16.0 | 16.0 | 16.0 |
| BOD sludge | 2nd flaskB2 | 7.0 | 7.0 | 12.0 | 14.0 | 15.0 | 16.0 |
| BOD sludge | mean B | 7.5 | 8.5 | 12.0 | 15.0 | 15.5 | 16.0 |
| BOD test subst. | 1st flask C1 | 104.2 | 148.9 | 199.5 | 235.2 | 246.2 | 247.2 |
| BOD test subst | 2nd flask C2 | 93.9 | 159.6 | 202.2 | 218.7 | 223.6 | 224.6 |
| BOD test subst | 1st fl.corr C1 -B | 96.7 | 140.4 | 187.5 | 220.2 | 230.7 | 231.2 |
| % degr | 2nd fl.corr C2 -B | 86.4 | 151.1 | 190.2 | 203.7 | 208.1 | 208.6 |
| % degr | 1st flask D1 | 34 | 49 | 66 | 78 | 81 | 81 |
| % degr | 2nd flask D2 | 30 | 53 | 67 | 72 | 73 | 73 |
| % degr | mead D | 32 | 51 | 67 | 75 | 77 | 77 |
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
