Lithium Citrate Tetrahydrate

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2016-11-17 to 2016-12-12

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Version / remarks:

2015

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

other: The preliminary test was negtive. Thus, performance of the main test was not necessary.

Preliminary test

The test item could not be ignited with a flame. The test item charred in the ignition flame. The performance of the main test was not necessary.

Interpretation of results:

GHS criteria not met

Conclusions:

The test item is not a readily combustible solid in the sense of UN Manual of Test and Criteria, Method N.1.
The test item is not a flammable solid according to chapter 2.71 of the GHS (CLP) regulations.

Reference 2

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2016-11-22 to 2016-11-22

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: Guideline VDI 2263, sheet 1 (Grewer-oven)

Deviations:

no

GLP compliance:

no

Key result

Test procedure:

other: 8 cm³ of the test item

Result:

negative outcome (no effect observed)

Individual results:

2.9 g of the test item were placed into the wire-basket.

The temperature of the test item showed a multistage endothermal effect at a temperature range of approx. 60-220 °C. At an oven temperature of approx. 240 °C an exothermal effect started. A second exothermal effect was observed at an oven temperature of approx. 345 °C.

The test item showed a discolouration from white to black and had swollen up during the test.

As the first exothermic process started above 220 °C no further testing is necessary.

Interpretation of results:

GHS criteria not met

Conclusions:

According to the guideline VDI 2263, sheet 1 (Grewer-Oven) no self-ignition temperature was observed up to 250 °C (first exothermal effect). Due to this result the test item does not have to be classified as self-heating substance.

Reference 3

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Reference 4

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the experience in production or handling shows that the substance does not react with water, e.g. the substance is manufactured with water or washed with water

Description of key information

The substance is not considered as flammable, flammable in contact with water, pyrophoric, and self-heating substance.

Key value for chemical safety assessment

Flammability:

not classified

Additional information

Flammability:

A test for flammable solids was conducted according to EU Test N.1 (Albemarle, 20160428, 2017). In the preliminary test, the test item could not be ignited with a flame. The test item charred in the ignition flame. The performance of the main test was not necessary. In conclusion the test item is not a readily combustible solid in the sense of UN Manual of Test and Criteria, Method N.1. The test item is not a flammable solid according to chapter 2.71 of the GHS (CLP) regulations.

Self heating temperature:
The self-heating temperature of the test item was determined in a study according to the guideline VDI, sheet 1 (Grewer-Oven). The temperature of the test item showed a multistage endothermal effect at a temperature range of approx. 60-220 °C. At an oven temperature of approx. 240 °C an exothermal effect started. A second exothermal effect was observed at an oven temperature of approx. 345 °C. As the first exothermic process started above 220 °C no further testing was necessary and the test item does not have to be classified as self-heating substance.

Pyrophoric properties:

The study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied.

Emission of flammable gases upon contact with water

The study does not need to be conducted because the experience in handling and use shows that the substance does not react with water.

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No 1272/2008:
In accordance with Annex I, Section 2.1, Section 2.2, Section 2.3, Section 2.7, Section 2.9, Section 2.10 Section 2.11, Section 2.12 of Regulation (EC) No 1272/2008 and UN GHS Rev 6 (2015) the substance has not to be classified as readily combustible solid in class 4 Division 4.1, self-heating substance in Class 4 Division 4.2, substances which in contact with water emit flammable gases in Class 4 Division 4.3, pyrophoric liquid, pyrophoric solid in class 4 Division 4.2, flammable gases in class 2 or as aerosol in class 2.