Registration Dossier
Registration Dossier
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EC number: 272-028-3 | CAS number: 68649-42-3
Endpoint summary
Administrative data
Link to relevant study record(s)
- Justification for data waiving:
- other:
Reference
Description of key information
Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts is an Lubricantor Greaseor Additive that is primarily used in petroleum oil. Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts was of no acute toxicity to laboratory animals exposed via the oral, inhalation and dermal route and unlikely to be ingested in any appreciable amount by humans. It was of low acute toxicity to animals exposed by either the inhalation or dermal route. Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts was not considered to be a skin sensitizer. Non-occupational post-application exposure may occur from the use of Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts in residential settings; however, exposure is expected to be minimal given the use scenario, timing of application and low likelihood of contact with sprayed areas. Incidental oral exposure (for example, hand-to-mouth exposure) from petroleum oil and outdoor household items is expected to be very minimal as Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts is aLubricantor Grease or Additive used to make oil. The available database was sufficient to conclude that there is a very low level of concern for the hazard following exposure to Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts and hence toxicokinetic study was considered for waiver in the absence of any data related to toxicokinetics of Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts.
Key value for chemical safety assessment
Additional information
Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts is anLubricantorGreaseor Additive that is primarily used in petroleum oil. Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts was of no acute toxicity to laboratory animals exposed via the oral, inhalation and dermal route and unlikely to be ingested in any appreciable amount by humans. It was of low acute toxicity to animals exposed by either the inhalation or dermal route. Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts was not considered to be a skin sensitizer. Non-occupational post-application exposure may occur from the use of Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts in residential settings; however, exposure is expected to be minimal given the use scenario, timing of application and low likelihood of contact with sprayed areas. Incidental oral exposure (for example, hand-to-mouth exposure) from petroleum oil and outdoor household items is expected to be very minimal as Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts is aLubricantorGreaseor Additive used to makeoil. The available database was sufficient to conclude that there is a very low level of concern for the hazard following exposure to Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts and hence toxicokinetic study was considered for waiver in the absence of any data related to toxicokinetics of Phosphorodithioic acid, O,O-di-C1-14-alkyl esters, zinc salts.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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