Registration Dossier
Registration Dossier
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EC number: 205-781-3 | CAS number: 151-05-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 971
Materials and methods
- Principles of method if other than guideline:
- Female albino rabbits received a single application of the test material to clipped skin which was covered with rubber sheeting for 24 hours. One rabbit was treated at 1 g/kg, 1 rabbit at 2 g/kg and 3 rabbits at 3 g/kg. The application was left in contact with the skin for 24 hours and the animals were then observed for 7 days.
- GLP compliance:
- no
Test material
- Reference substance name:
- α,α-dimethylphenethyl acetate
- EC Number:
- 205-781-3
- EC Name:
- α,α-dimethylphenethyl acetate
- Cas Number:
- 151-05-3
- Molecular formula:
- C12H16O2
- IUPAC Name:
- 1,1-dimethyl-2-phenylethyl acetate
- Test material form:
- solid
Constituent 1
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 3 000 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
