Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-707-9 | CAS number: 162353-70-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects on microorganisms up to the limit of water solubility, read across.
Key value for chemical safety assessment
Additional information
Data on the toxicity of the target substance Fatty acids, C18-unsatd., dimers, reaction products with fatty acids, C14-18 and C16-18-unsatd. and propylidynemethanol (CAS 162353-70-0) to aquatic microorganisms are not available. The assessment was therefore based on a study conducted with the structurally similar substanceFatty acids, C14-18 and C18-unsatd., branched and linear, esters with trimethylolpropane (CAS 85005-23-8) as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Further justification is given within the overall summary chapter 6.1 and within the analogue justification in IUCLID section 13.
The toxicity of the source substance Fatty acids, C16-18 (even numbered) and C18-unsatd., branched and linear, di- and triesters with trimethylolpropane (former CAS 85005-23-8) to Pseudomonas putida was tested in a cell multiplication inhibition test according to ISO 10712 (Safepharm Laboratories Ltd., 1997). The test concentration in the limit test was 10000 mg/L (Water Accommodated Fraction (WAF)). No effects on the growth of Pseudomonas putida was observed and thus an EL10 and an EL50 (16 h) > 10000 mg/L (WAF loading rate) were reported.
Based on the results of the read across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) it is assumed that Fatty acids, C18-unsatd., dimers, reaction products with fatty acids, C14-18 and C16-18-unsatd. and propylidynemethanol has no inhibitory effects on aquatic microorganisms activity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
