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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
Identification: FAT 20011/E TE Lot. 1309023
Appearance: Blue powder
Water solubility:
2 g/L
Conc. based on:
test mat.
Temp.:
20 °C
Remarks on result:
other: pH not specified

Preliminary Visual Estimation of the Water Solubility

Appearance of the test mixtures in the preliminary test

Amount of the test item in mg

Total volume in ml

Appearance of mixture

 

10

5

undissolved

10

dissolved

50

dissolved

The preliminary visual experiments showed that the water solubility of the test item is about 1 g/L

Flask-Method

Water solubility of the test item – experiments A to D

 

Experiment

A

B

C

D(blank)

Amount of test item(mg)

500

500

500

---

Stirring time at 30 °C (h)

24

48

72

72

Measured concentration (µg/l)

 5.0

 5.0

 4.7

 ---

Aliquot

0.025/10

0.025/10

0.025/10

0.025/10

Water solubility(g/l)

2.0

2.0

1.9

---

Average experiments A to C: 2.0 g/l

- The recovery of 101.2 % indicated sufficient accuracy of the analytical method.

Conclusions:
The water solubility of FAT 20011/E at 20 °C was determined to be 2.0 g/l.
Executive summary:

The purpose of the study was determination of the water solubility of FAT 20011/E according to the European Commission Regulation (EC) No.440/2008, A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility were used to performed the experiment. Flask method was used for this purpose. based on the findings of the study, the water solubility of FAT 20011/E at 20 °C was determined to be 2.0 g/l.

Description of key information

The purpose of the study was determination of the water solubility of FAT 20011/E according to the European Commission Regulation (EC) No.440/2008, A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility were used to performed the experiment. Flask method was used for this purpose. based on the findings of the study, the water solubility of FAT 20011/E at 20 °C was determined to be 2.0 g/l.

Key value for chemical safety assessment

Water solubility:
2 000 mg/L
at the temperature of:
20 °C

Additional information