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Diss Factsheets
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EC number: 246-014-2 | CAS number: 24085-08-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
One key study in accordance with GLP and OECD 201 (Alga, Growth Inhibition Test).
The effect of the test item on the growth of Pseudokirchneriella subcapitata was investigated over a 72-Hour period and based on the time-weighted mean measured test concentrations.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 51 mg/L
- EC10 or NOEC for freshwater algae:
- 15 mg/L
Additional information
Chemical analysis of the test preparations at 0 hours showed measured test concentrations to range from 5.93 to 97.0 mg/L. Given that analysis of the test preparations taken from the range- finding test showed a decline in measured concentration occurred over the 72-Hour test period, it was considered likely that the test item was unstable under test conditions. It was therefore considered appropriate to prepare additional test samples for analysis at 24 and 48 hours in order to better define the rate of decline in measured concentration. Analysis of these additional test preparations showed a decline in measured concentration in the range of 3.49 to 90.4 mg/L at 24 hours and 1.22 to 80.4 mg/L at 48 hours. A further decline in the range of 0.0762 to 24.1 mg/L was observed at 72 hours.
Given this decline in measured test concentrations it was considered justifiable to base the results on the time-weighted mean measured test concentrations in order to give a "worst case" analysis of the data.
Exposure of Pseudokirchneriella subcapitata to the test item gave the following results based on the time-weighted mean measured test concentrations:
Response Variable |
EC50 (mg/L) |
95% Confidence Limits (mg/L) |
No Observed Effect Concentration (NOEC)(mg/L) |
Lowest Observed Effect Concentration (LOEC)(mg/L) |
GrowthRate |
51 |
* |
15 |
34 |
Yield |
28 |
25 - 32 |
5.9 |
15 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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