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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Hydrolysis

The base catalyzed second order hydrolysis rate constant was determined using a structure estimation method of the test chemical (authoritative databases, 2017). The second order hydrolysis rate constant of test chemical was determined to be 6.3L/mol-sec with a corresponding half-lives of 3.5 yrs and 130 days at pH 7 and 8, respectively. Based on the half-life values, it is concluded that the test chemical is not hydrolysable.

Additional information

Hydrolysis

Various experimental key and supporting studies for the test chemical were reviewed for the hydrolysis end point which are summarized as below:

 

In an experimental key study from authoritative database (2017),the base catalyzed second order hydrolysis rate constant was determined using a structure estimation method of the test chemical. The second order hydrolysis rate constant of test chemical was determined to be 6.3 L/mol-sec with a corresponding half-lives of 3.5 yrs and 130 days at pH 7 and 8, respectively.

 

In an another study, the half-life value of test chemical in water was determined at different pH. The hydrolysis half-life value of test chemical was determined to be 10 yrs, 6 yrs, 229 days and 23 days at pH 5, 7, 8 and 9, respectively.

 

In a prediction done using the HYDROWIN v2.00 program of Estimation Programs Interface (2017) prediction model was used to predict the hydrolysis half-life of test chemical. The estimated half-life of test chemical was determined to be 3.505 yrs and 128.021 days at pH 7.0 and 8.0 (at 25ᵒC) respectively, indicating that it is not hydrolysable.

 

For the test chemical, the half-life and base catalyzed second order hydrolysis rate constant was determined of the test chemical (HSDB, 2017). The second order hydrolysis rate constant of test chemical was determined to be 0.089L/mol-sec with a corresponding half-lives of 2.5 yrs and 90 days at pH 7 and 8, respectively.

 

In an another study from authoritative database (2017), the half-life and base catalyzed second order hydrolysis rate constant of the test chemical was determined using a structure estimation method. The second order hydrolysis rate constant of test chemical was determined to be 0.12 L/mol-sec with a corresponding half-lives of 1.7 yrs and 64 days at pH 7 and 8, respectively.

 

On the basis of above results for test chemical (from handbook, authoritative and modelling databases,2017), it can be concluded that the half-life value of test chemical was determined to be ranges from 23 days to 10 yrs, respectively, indicating that the test chemicalis not hydrolysable.