Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

Currently viewing:

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: data have not undergone any evaluation by the European Commision; no dose information and no criteria for interpretation of the result are stated in the dataset.

Data source

Reference
Reference Type:
other: IUCLID dataset
Title:
IUCLID dataset. Existing Chemical Substance ID: 616-38-6. EINECS Name: dimethyl carbonate
Author:
European Commission (ed.)
Year:
2000
Bibliographic source:
ESIS (European Chemical Substances Information System); dataset online available at http://ecb.jrc.ec.europa.eu/iuclid-datasheet/616386.pdf

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: no data
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
no data
IUPAC Name:
no data

Test animals / tissue source

Species:
rabbit

Test system

Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
no data
Observation period (in vivo):
no data
Number of animals or in vitro replicates:
no data

Results and discussion

In vivo

Results
Remarks on result:
other: overall irritation/corrosion results: no data
Other effects:
no data

Applicant's summary and conclusion

Interpretation of results:
slightly irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
The IUCLID dataset reports that dimethyl carbonate is slightly irritating to the rabbit eye. However, the study result is not usable for the classification of the substance since no dose information and no criteria for interpretation of the result are stated.