Registration Dossier
Registration Dossier
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EC number: 931-250-7 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Justification for read across:
There are no specific experimental data available for MK1 diesel fuel. Compositional and physico-chemical data show that MK1 Diesel Fuel is very similar to Kerosine. It is considered appropriate, therefore, to read across from the Kerosine data to MK1 Diesel Fuel. In that respect, the conclusions on the ecological toxicity endpoints for MK1 Diesel Fuel will be the same for those of Kerosine. Further discussion on ecological toxicity will concern Kerosine, and data endpoints that are waived for Kerosine will be waived for MK1 Diesel Fuel.
Short-term toxicity to aquatic invertebrates has been filled by read-across of measured data from kerosine. It is supported in a weight of evidence approach by a calculated value using composition information derived from two dimensional gas chromatography in conjunction with the PETROTOX model.
In a semi-static read-across 96 -hour acute rainbow trout (Oncorhynchus mykiss) test (OECD 203; KS=1), 7 animals/dose were exposed to solvent, naphtha (petroleum), heavy aromatic kerosine at nominal concentrations of 0, 0.2, 0.7, 2.0, 5.0, 17.0, and 50.0 mg/L. Some fish were observed swimming abnormally and immobilisation was also observed. The LL50 was 2 to 5 mg/L. The NOEL is 2.0 mg/L (Shell, 1994).
In four reliable supporting read-across semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss) studies, the LL50 ranged from 2 to 100 mg/L; with the NOELs ranging from 6.8 to 10 mg/L (Exxon 1995a,b,c, Shell 1995).
Supporting PETROTOX data shows that the estimated freshwater fish 96 -hour LL50 value is 63.19 mg/L (Redman et al., 2010b).
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