Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according OEDC/EU guidelines.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1991

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 401
GLP compliance:
yes (incl. QA statement)
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(2-aminoethyl)[(6-chloropyridin-3-yl)methyl]amine
EC Number:
600-261-6
Cas Number:
101990-44-7
Molecular formula:
C8H12ClN3
IUPAC Name:
(2-aminoethyl)[(6-chloropyridin-3-yl)methyl]amine

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
physiological saline

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 200 - < 500 mg/kg bw

Applicant's summary and conclusion