Registration Dossier
Registration Dossier
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EC number: 210-514-9 | CAS number: 617-48-1
Endpoint summary
Administrative data
Description of key information
Additional information
Read across to fumaric acid is considered valid as the metabolic route for fumaric acid is through malic acid. Therefore, to achieve biodegradation in excess of 60% implies that malic acid is also readily biodegradable. Fumaric acid is less water soluble and also requires one further metabolic step than malic acid; it is likely that malic acid biodegrades faster.
Modelling with EPISuite confirms high biodegradation for this class of natural substance.
D and L isomers of malic acid have the same metabolic profile (see toxicokinetic assessement)
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