Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-152-2 | CAS number: 78-87-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
Overall these studies provide no evidence that 1,2-dichloropropane selectively targets the male or female reproductive systems or the developing embryo/fetus.
Lowest NOAEL values :
70 mg/kg bw/day for fertility
150 mg/kg bw for teratogenicity
Justification for classification or non-classification
Based on the results of the reported studies and taking into account the literature, 1,2-dichloropropane does not meet the classification criteria as toxic for reproduction.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
