Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-532-3 | CAS number: 107-92-6
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 981
- Report date:
- 1981
- Reference Type:
- review article or handbook
- Title:
- Report to RIFM, 01 July 1977
- Author:
- Epstein Wl Report to RIFM, 01 July 1977 (cited from Opdyke 1979)
- Year:
- 1 977
- Bibliographic source:
- Research Institute for Fragrance Materials, cited in Opdyke (1981)
- Report date:
- 1977
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Maximization test according to Kligman and Epstein (1975)
- GLP compliance:
- no
- Type of study:
- other: maximization test
Test material
- Reference substance name:
- Butyric acid
- EC Number:
- 203-532-3
- EC Name:
- Butyric acid
- Cas Number:
- 107-92-6
- Molecular formula:
- C4H8O2
- IUPAC Name:
- butyric acid
- Details on test material:
- - Name of test material (as cited in study report): n-butyric acid, n-butanoic acid (RIFM no. 77-60)
- no further information reported
Constituent 1
In vivo test system
Test animals
- Species:
- human
Results and discussion
Any other information on results incl. tables
No sensitization reaction was produced by the test substance (1% in petrolatum) in the test system used.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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