Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The substance showed no skin and eye irritating properties.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

In a dermal irritation/corrosion GLP study according to OECD 404, in which 3 female rabbits (Crl: KBL(NZW)BR) were exposed to Diethyleneglycol, propoxylated, no irritation was noted. There were no systemic intolerance reactions. According to classification criteria Diethyleneglycol, propoxylated is not an irritant to the skin.

In an eye irritation GLP study according to OECD 405, in which 3 male rabbits (New Zealand white Crl: KBL (NZW) SPF) were exposed to Diethyleneglycol, propoxylated, no irritation was noted. There were no reactions. According to classification criteria Diethyleneglycol, propoxylated is not an irritant to the eye.

Justification for classification or non-classification

Based on the results of a dermal irritation/corrosion and a eye irritation study, classification is not warranted in the EU.