Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 237-301-3 | CAS number: 13732-62-2
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets generally accepted scientific principles, but data not suitable for assessment due to short-term observation period
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Comparative effects of heterocyclic compounds on inhibition of lettuce fruit germination
- Author:
- Reynolds T
- Year:
- 1 989
- Bibliographic source:
- J Exp Bot 40(121): 391-404
- Reference Type:
- publication
- Title:
- Comparative effects of heterocyclic compounds on inhibition of lettuce fruit germination
- Author:
- Reynolds T
- Year:
- 1 989
- Bibliographic source:
- J Exp Bot 40: 391-404. As cited in BUA (1990). BUA Substance report 56: Morpholine, status Dec. 1990. Hirzel Stuttgart, Germany.
Materials and methods
- Principles of method if other than guideline:
- Germination inhibition test with Lactuca sativa (method described in Reynolds 1975, 1977)
- GLP compliance:
- no
Test material
- Reference substance name:
- Morpholine
- EC Number:
- 203-815-1
- EC Name:
- Morpholine
- Cas Number:
- 110-91-8
- Molecular formula:
- C4H9NO
- IUPAC Name:
- morpholine
- Details on test material:
- - Name of test material (as cited in study report): morpholine
- Analytical purity: no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- no
Test organisms
- Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: lettuce
- Plant family: Compositae (Asteraceae)
- Variety: Lactuca sativa L. cv. Great Lakes
Study design
- Test type:
- other: seed germination
- Study type:
- laboratory study
- Substrate type:
- other: agar
- Total exposure duration:
- 3 d
Test conditions
- Test temperature:
- 30 °C
- Details on test conditions:
- TEST SYSTEM
- Test container (type, material, size): plastic containers sealed with snap-on lids - Nominal and measured concentrations:
- - test concentrations not stated
- control included
Results and discussion
Effect concentrations
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 383 other: mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- germination
- Remarks on result:
- other: EC50: 383±78 mg/L; original data given: EC50: 4.4±0.9 mol/m³
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
