Quaternary ammonium compounds, benzyl C12-C16 (even numbered)-alkyldimethyl chlorides

Additional physico-chemical information

Link to relevant study record(s)

Reference

Endpoint:

other:

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 09 October, 2006 to 08 June, 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Principles of method if other than guideline:

GLP, according to CIPAC Handbook Volume J, MT46.3 (2000). Glass bottle with screw cap, capable for gas tight sealing. Storage will be carried out for 14 d in an incubator in the nominal range of 54 ± 2°C in the dark. An LC-MS scan will be performed before and after storage. Any additional peak will be identified and quantified if possible.

GLP compliance:

yes (incl. QA statement)

Results:

Accelerated Storage Procedure

No significant change in the test substance was found when stored for 14 d at 50°C.

Conclusions:

Under the study conditions, the test substance is considered to be stable.

Executive summary:

A study was conducted to determined the stability of the test substance, C12-16 ADBAC (49.2% active) according to the accelerated storage procedure. Test substance was stored in glass bottle with screw cap, capable for gas tight sealing for 14 d in an incubator at the temperature of 54 ± 2°C in the dark. An LC-MS scan was performed before and after storage. No significant change in the test substance was found when stored for 14 d at 50°C. Under the study conditions, the test substance is considered to be stable (Lange, 2007).

Description of key information

The stability was determined according to the accelerated storage procedure (Lange J, 2007).

Additional information

The test substance was found to be stable when stored for 14 d at 50°C.