Registration Dossier
Registration Dossier
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EC number: 295-714-4 | CAS number: 92128-22-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of the substance to Daphnia magna was investigated in a semi-static test according to EC No 440/2008, Method C.2 'Acute toxicity for Daphnia' (2008) which is equivalent to OECD Guideline for Testing of Chemicals No. 202 'Daphnia sp., Acute Immobilisation Test (adopted April 13, 2004). After 48 hours of exposure an EC50 of 0.111 mg/L (measured) was determined by probit analysis.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.111 mg/L
Additional information
The concentration of the test substance after 24 h of exposure is only of 6.5 - 22.9 % of nominal values (Currenta, 2009b). The substance is hydrolysis stable at pH 7 and 25 °C (ref. chapter 5.1.2) and hence no loss due to hydrolysis is expected. The high adsorption coefficient (log Koc of ca. 8.3, ref. chapter 5.4.1) may explain the difference between nominal concentrations and measured concentrations, due to adsorption on glass of the aquarium and on the filters during sample preparation for analytical monitoring. Thus the result based on measured concentrations can be considered as a worst case situation.
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