Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-616-8 | CAS number: 68391-03-7
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 April 2020
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The saturated solution of test substance was prepared in n-octanol and the quantification of the saturated solution was performed plotting the nD20 (refraction index) vs. known concentrations of reference samples.
- GLP compliance:
- not specified
- Key result
- Medium:
- n-octanol
- Solubility:
- ca. 188 g/L
- Temp.:
- 20 °C
- Details on results:
- The saturated solution of test substance was estimated to be 188 g/L at 20°C for n-octanol.
- Conclusions:
- Under the study conditions the n-octanol solubility of the test substance was determined to be 188 g/L at 20°C.
- Executive summary:
A study was conducted to determine the n-octanol solubility of the test substance, C12 -18 TMAC (96.8% active), using the refraction index method for saturated solution of test substance. Under the study conditions, the n-octanol solubility of the test substance was determined to be 188 g/L at 20°C (Holtin, 2020).
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Study period:
- 17 April 2020
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Refer to the Quaternary ammonium salts (QAS) category or section 13 of IUCLID for details on the category justification.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The saturated solution of test substance was prepared in n-octanol and the quantification of the saturated solution was performed plotting the nD20 (refraction index) vs. known concentrations of reference samples.
- GLP compliance:
- not specified
- Key result
- Medium:
- n-octanol
- Solubility:
- 169 g/L
- Temp.:
- 20 °C
- Details on results:
- The saturated solution of test sunstance was estimated to be 169 g/L at 20°C for n-octanol
- Conclusions:
- Under the study conditions, the n-octanol solubility of the test substance was determined to be 169 g/L at 20°C.
- Executive summary:
A study was conducted to determine the n-octanol solubility of the read across substance, C12 -14 TMAC (97% active), using the refraction index method for saturated solution of test substance. Under the study conditions, the n-octanol solubility of the test substance was determined to be 169 g/L at 20°C (Holtin, 2020).
Referenceopen allclose all
Result:
Sample
|
g/L |
|
|
Calibration
|
126.7
|
1.4359
|
|
Calibration
|
101.4
|
1.4345
|
|
Calibration
|
76.0
|
1.4333
|
|
Calibration
|
50.7
|
1.4320
|
|
Calibration
|
25.3
|
1.4308
|
|
C12-18 TMAC saturated
|
187.8
|
1.4389 |
Result:
Sample
|
g/L
|
|
|
Calibration
|
122.6
|
1.4367
|
|
Calibration
|
98.1
|
1.4352
|
|
Calibration
|
73.6
|
1.4337
|
|
Calibration
|
49
|
1.4324
|
|
Calibration
|
24
|
1.4310
|
|
C12-14 TMAC saturated
|
168.5
|
1.4393 |
Description of key information
The solubility in organic solvents of the test substance was determined using refractometric method by plotting the nD20 (refraction index) vs. known concentrations of reference samples (Holtin, 2012).
Key value for chemical safety assessment
- At the temperature of:
- 20 °C
- Solubility in organic solvents at 20°C:
- 188 g/L
Additional information
The n-octanol solubility value of another test sample containing majorly C12-14 chains was determined to 169 g/L at 20 °C. The n-octanol solubility of the more representative test sample has been considered as the key value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
