Registration Dossier
Registration Dossier
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EC number: 285-206-0 | CAS number: 85049-36-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data given.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
- Report date:
- 1986
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- yes
- Remarks:
- ; only female animals tested; lack of details on test substance and methodological details
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Ethyl oleate
- EC Number:
- 203-889-5
- EC Name:
- Ethyl oleate
- Cas Number:
- 111-62-6
- Molecular formula:
- C20H38O2
- IUPAC Name:
- ethyl octadec-9-enoate
- Details on test material:
- - Name of test material (as cited in study report): only trade name given
- Lot No. 36
- Analytical purity: no data
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- NMRI
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Source: no data
- Weight at study initiation: 20 g
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Details on oral exposure:
- MAXIMUM DOSE VOLUME APPLIED: 5 mL/kg bw
- Doses:
- 5 mL/kg bw equivalent to 4360 mg/kg bw calculated with a density of 0.872 g/mL for ethyl oleate
- No. of animals per sex per dose:
- 5
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 4 360 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: converted from 5 mL/kg bw based on a density of 0.872 g/mL
- Mortality:
- No mortality occurred during the study period.
- Clinical signs:
- other: No clinical signs occurred during the study period.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- CLP: not classified
DSD: not classified
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