Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 267-023-8 | CAS number: 67762-55-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water: simulation test
In accordance with Column 2 Specific Rules for Adaptation from Column 1 under Annex IX, simulation testing on ultimate degradation in surface water does not need to be conducted if the substance is highly insoluble in water. Two water solubility studies have been conducted at two different laboratories. In both studies, it was not possible to determine the water solubility, as it was not analytically feasible. Use of QSARs on representative structures also indicates that the substance is insoluble. The OECD 309 TG specifies that selected concentrations for running this study should ideally be in the range of 0.001-0.1 mg/L. However, these concentrations cannot be achieved with this substance. Therefore, this substance is considered highly insoluble in water and this endpoint can be waived.
Biodegradation in sediment: simulation test
Under Section 2 of Annex XI, and with respect to Article 13(3), it is considered that it is not technically possible to run the simulation test. According to OECD 308, prior to running this study, it is necessary to know the solubility in water (according to OECD 305), the n-octanol/water partition coefficient (Kow) (according to OECD 107 or 117) and the adsorption coefficient (Koc) (according to OECD 106). However, the substance is highly insoluble in water, and its water solubility cannot be analytically determined with any level of accuracy or reliability. Therefore, it is not possible to meet the first of these abovementioned criteria. In consideration of the other relevant physico-chemical properties, the Log Kow has been determined to be >10, and no reference standard is currently available to allow a more precise determination. Equally, the Log Koc has been determined to be >5.63. As these values cannot be more accurately determined with current analytical capabilities, these pre-requisites for the OECD 308 are not met.
Furthermore, OECD 308 states that it is applicable to slightly volatile, non-volatile, soluble and poorly water-soluble compounds. The guidance does not include highly insoluble compounds within the scope of applicable substances. Therefore, it is considered that sediment simulation testing methods are not appropriate to this substance based on water solubility. In further consideration of the OECD 308 method, it should be noted that it does allow for the use of solvents for the addition of test substance into the system, which should not exceed 1% v/v. However, in an OECD 301B study, it was necessary to use a greater volume of solvent than this to obtain a meaningful test result. If a similar method were employed in a sediment simulation test, it would be necessary to use of solvents and dissolution substances at concentrations above those prescribed in OECD 308. Therefore, the use of solvents is not considered appropriate in this case. As such, it is considered that the study is not technically feasible.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.