Registration Dossier
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EC number: 254-879-2 | CAS number: 40306-75-0
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
According to QSAR predictions the BCF value of 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is estimated to be
6.384377 which does not exceed the EPA bioconcentration criteria of1000. From this it is concluded that 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is not expected to bioaccumulate in the food chain.
Key value for chemical safety assessment
- BCF (aquatic species):
- 6.384 dimensionless
Additional information
Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration.
The estimated BCF values for 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid by the reliable sources QSAR ,PBT profiler, EPI suite and Scifinder are presented below respectively
Sr. No |
Endpoint name |
Value |
1 |
BCF | 6.384377 |
| 2 | BCF | 3.2 |
| 3 | BCF | 3.162 |
| 4 | BCF | 1 |
Based on the above it can be concluded that the substance is classified as non bioaccumulative in nature as the values
does not exceed the EPA bioconcentration criteria of1000 and therefore is non bioaccumulative in nature according CLPregulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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