Registration Dossier
Registration Dossier
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EC number: 272-250-0 | CAS number: 68784-48-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Quality of whole database:
- Extensive data has been determined for the key degradation products showing an absence of systemic toxic effects, rapid metabolism of organic components and lack of accumulation of titanium salts. Performing further animal studies is not justified on the basis of the existing toxicity review.
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
Extensive data has been determined for the key degradation products showing an absence of systemic toxic effects, rapid metabolism of organic components and lack of accumulation of titanium salts. Performing further animal studies is not justified on the basis of the existing toxicity review.
Effects on developmental toxicity
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Additional information
Extensive data has been determined for the key degradation products showing an absence of systemic toxic effects, rapid metabolism of organic components and lack of accumulation of titanium salts. Performing further animal studies is not justified on the basis of the existing toxicity review.
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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