N,N'-bis(2,2,6,6-tetramethylpiperidin-4-yl)hexane-1,6-diamine

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.024 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.243 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.002 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

21.75 mg/L

Assessment factor:

1

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.09 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.009 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.004 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

The test substance has shown to be harmful to algae, daphnids and microorganisms, while no toxic effects of the test substance were recorded for fish.

The key study for fish reported an LC50(96h)>100 mg/L, with a supporting study at 346 mg/L. Effects on algae were reported from EC50(72h) values >75.7 mg/L, effects on microorganisms (Pseudomonas putida, 16.7h) were reported at 38.85 mg/L. The most sensitive organisms were daphnids with effects on immobilisation (EC50(48h)) at 24.3 mg/L. The only NOEC was reported within the algae study with a 72-h value of 9.4 mg/L, an EC10(16.7h) for Pseudomonas putida was reported at 21.75 mg/L.

Aquatic PNECs were derived from acute data for the most sensitive group, the daphnids, using an assessment factor of 1000 since no chronic studies on fish and invertebrates were available. Similarly, the PNEC marine water was determined from freshwater studies.

PNEC sediment and soil had to be calculated via equilibrium partitioning method under usage of the Koc value, similarly the PNECs freshwater and marine water with a rho soil of 1150 kg/m3. A koc value of 1.076 L/kg was applied, with a resulting Ksoil-water of 0.23. A conversion factor from wet to dry weight of soils was applied (factor of 1.13).

Conclusion on classification

The data for the test substance indicate the substance to be acutely harmful to aquatic organisms (EC50=24.3 mg/L for daphnids and EC50=75.7 mg/L for algae). The NOEC(72h) for algae was 9.4 mg/L, a chronic study on the most sensitive aquatic group (aquatic invertebrates) is not available. The substance is not readily biodegradable (3 to 23% in 28 days). Hence, the substance has to be classified as R52/53 under DSD-DPD and as chronic III (H412) under GHS (CLP).