Registration Dossier
Registration Dossier
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EC number: 248-660-0 | CAS number: 27794-93-0
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Based on the measured BCF, ATMP and its salts are not expected to bioaccumulate.
Key value for chemical safety assessment
Additional information
Three reliable results, measured with the parent acid (ATMP, CAS 6419-19-8), are available. There is a report of bioaccumulation of ATMP in carp, bioconcentration factor in the exposure phase of –<4 - 22 (EG&G, 1976a). Two other results were reported in the 1993 SIDS data set: these are assumed to be reliable although the original reports were not available for review. The results are BCF = 5.2 – 17.7 and BCF = 18 – 24, both measured for ATMP acid in Brachydanio rerio (zebra fish). The key result is read across to this substance.
This substance is a member of a category of various ionised forms of the acid 6419-19-8. The main assumption is that potassium is not significant in respect of all the properties under consideration. In dilute aqueous conditions of defined pH a salt will behave no differently to the parent acid, at identical concentration of the particular speciated form present and will be fully dissociated. Hence some properties (measured or expressed in aqueous media, e.g. ecotoxicity) for a salt can be directly read across (with suitable mass correction) to the parent acid and vice versa. In the present context the effect of the counter-ion (potassium) will not be significant. In biological systems and the environment, polyvalent metal ions will be present, and the phosphonate ions show very strong affinity to them
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