Registration Dossier
Registration Dossier
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EC number: 609-724-7 | CAS number: 39605-45-3
Endpoint summary
Administrative data
Description of key information
No data are available for the substance. However, atrazine (2-chloro-4-ethylamine-6-isopropylamine- 1,3,5-triazine, CAS Nr 1912-24-9) has the same base structure: It is a triazine, diamine, and is at the same position chlorinated. While the test substance carries two secondary amine side chains, atrazine has two primary amines as side chains, both times in meta-position. Based on this structural similarity to atrazine it can be assumed that the substance has similar effects to human health. In a 1-yr study in dogs atrazine induced severe cardiac effects (in accordance to IUCLID Dataset Atrazine, Feb. 18, 2000).
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
Regulation (EC) 1272/2008
As atrazine is classified as STOT Rep. 2 in Annex VI of regulation (EC) 1272/2008 this classification is taken for the test article as well, based on the structural similarity and due to the lack of data with the test article itself. The cardiovascular system was identified as target organ.
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