6-hydroxy-1H-pyrimidin-4-one

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

21-Jun-2010 to 12-Aug-2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study conducted in compliance with OECD and EU Guidelines.

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

GLP compliance:

no

Type of method:

OECD harmonised ring method

Surface tension:

67 mN/m

Temp.:

20.2 °C

Conc.:

1.005 g/L

The calibration factorΦ_bwas determined to be 1.0380 for double distilled water (Table1). The data are part of Harlan Laboratories' instruments files and a copy is presented in the raw data of thepresent study.

 

Table 2 shows the individual measurements for the surface tension of the aqueous test item solution. From these, the mean and the corrected value for the given solution were calculated and are also shown in Table 2. The tabulated values represent rounded results obtained from calculation using the exact raw data.

Table 1       Determination of the Calibration Factor Using Water

Time expired	Temperature	Surface tension [mN/m]		Calibration factor
		measured	mean value calculated from the bold values
[hours:min]	[°C]		σg	Φb
00:31	19.8	70.2	70.12	1.0380
00:32	19.8	70.2
00:34	19.8	70.1
00:35	19.8	70.1
00:36	19.8	70.0
00:37	19.8	70.1

 

with

σ_o     =      72.78 mN/m at 19.8°C

Φ_b    =      σ_o/σ_g

Φ_b    =      72.78 / 70.12 = 1.0380

 

where

 

Φ_b    =      calibration factor

σ_o     =      the surface tension of water at the test temperature

σ_g     =      measured value of the surface tension of water

                  at the test temperature

 

 

Table2       Determination of Surface Tension for the Test Item Solution

Time expired	Temperature	Surface tension	[mN/m]
		measured	mean value calculated from the bold values	mean value corrected for calibration	σ1corrected for Harkins-Jordan
[hours:min]	[°C]	[mN/m]	(σ*)	(σ 1)	(σ)
First sample
00:31	20.2	65.8	65.67	68.16	67.90
00:32	20.2	65.8
00:33	20.2	65.7
00:34	20.2	65.6
00:35	20.2	65.6
00:36	20.2	65.5
Second sample
00:34	20.1	64.2	64.05	66.48	66.02
00:35	20.1	64.2
00:36	20.1	64.1
00:37	20.1	64.0
00:39	20.1	63.9
00:40	20.1	63.9

 

Mean value from both samples:                                                σ = 67.0 mN/m

 

calibration factor 1.0380

 

Conclusions:

The result is considered to be reliable without restrictions.

Executive summary:

 

 

Description of key information

67.0 mN/m, 20.2 °C ± 0.1 °C, 1g/L, OECD 115, OECD harmonised ring method, Weissenfeld, 2010

Key value for chemical safety assessment

Surface tension:

67

in mN/m at 20°C and concentration in mg/L:

1 005

Additional information

The determination of the surface tension of an aqueous solution of the substance was based on the OECD Guideline No. 115.

The result is considered adequate and reliable.